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Search Results for " airway smooth muscle "

ターゲット

10

阻害剤

2

天然化合物

4

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T1083L Theophylline monohydrate Quibron HDAC , PDE , Adenosine Receptor
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ...
T16564 PPADS tetrasodium P2X Receptor , Na+/Ca2+ Exchanger
PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle and is neuroprotective against glutamate/NMDA toxicity.PPADS tetrasodiuma in...
T68129L1 Picumeterol FA Picumeterol FA(130641-36-0 Free base) Adrenergic Receptor
picumeterol FA is a potent and selective β2-adrenergic receptor agonist. In in vitro and in vivo tests, picumeterol FA produces long-lasting airway smooth muscle relaxation. picumeterol FA is a pure R-enantiomer and can ...
T6707 Tiotropium Bromide hydrate BA-679 BR hydrate,BA 679BR AChR
Tiotropium Bromide hydrate (BA-679 BR hydrate) is a potent anticholinergic and bronchodilator, serving as a muscarinic receptor antagonist, specifically targeting mAChR. It is developed for treating chronic obstructive a...
T32156 Indimilast
Indimilast is used to inhibit phosphodiesterase IV that regulates lung inflammation and causes bronchiectasis by increasing intracellular cyclic adenosine 3', 5'-monophosphate in airway smooth muscle and inflammatory cel...
T68129 Picumeterol GR 114297A Adrenergic Receptor
Picumeterol(GR 114297A) is a potent and selective β2 adrenergic receptor agonist. In vitro and in vivo trials, Picumeterol produced long-lasting airway smooth muscle relaxation. Picumeterol is a pure R enantiomer that ca...
T37228 (±)8(9)-EpETE
Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE , relaxes vascular and airway smooth muscle b...
T11240 Ethacrynic acid D5 Others
Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effec...
T60511 Theophylline sodium glycinate
Theophylline (1,3-Dimethylxanthine) sodium glycinate is a potent inhibitor of phosphodiesterase (PDE) that inhibits PDE3 activity to relax airway smooth muscle. Theophylline sodium glycinate can be used for the research ...
T60332 Methacholine bromide
Methacholine bromide (Acetyl-β-methylcholine bromide) is a potent muscarinic-3 (M3) agonist that specifically acts on acetylcholine receptors located on smooth muscle, inducing bronchoconstriction and narrowing of the ai...
カタログ番号 製品名 別名 ターゲット
T1083 Theophylline Theo-24,1,3-Dimethylxanthine Endogenous Metabolite , HDAC , PDE , Adenosine Receptor , Autophagy
Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3...
T4S0998 Trifolirhizin TNF , Tyrosinase
Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirhizin possesses potential anti-inflammatory and anti-cancer ...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-01210 IL-33 Protein, Mouse, Recombinant Mouse E. coli
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi...
TMPH-02540 GRK2 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to...
TMPH-03753 MYLK Protein, Human, Recombinant (His) Human E. coli
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos...
TMPH-02526 Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth...